produces large quantities of averufin instead of aflatoxin
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Type Strain
no
Preceptrol®
no
Comments
Aflatoxin biosynthesis
Medium
ATCC® Medium 325: Malt extract agar (Blakeslee's formula)
Growth Conditions
Temperature: 24.0°C
Name of Depositor
JA Donkersloot
Isolation
Mutant derived from ATCC 15517
References
Singh R, Hsieh DP. Aflatoxin biosynthetic pathway: elucidation by using blocked mutants of Aspergillus parasiticus. Arch. Biochem. Biophys. 178: 285-292, 1977. PubMed: 836036
Gorst-Allman CP, et al. Biosynthesis of averufin in Aspergillus parasiticus from [13 C]-acetate. J. Chem. Soc. Chem. Commun. 1976: 916-917, 1976.
Lin MT, et al. Conversion of averufin into aflatoxins by Aspergillus parasiticus. Biochemistry 12: 5167-5171, 1973. PubMed: 4792300
Donkersloot JA, et al. Isolation of averufin from a mutant of Aspergillus parasiticus impaired in aflatoxin biosynthesis. Biochem. Biophys. Res. Commun. 47: 1051-1055, 1972. PubMed: 5029856